From Algoma, Wisconsin, USA:
I am a 56 year old male with type 1 diabetes. I was originally diagnosed as a type 2 and went through all five classes of oral medications with no success. I then progressed to insulin with multiple daily injections and finally have been placed on an insulin pump. When I was first diagnosed with diabetes, I had a C-Peptide of 1.9. The laboratory range was 1.1-4. My last C-Peptide was 1.0 again with the laboratory range of 1.1-4. It was then that my diagnosis was changed from type 2 to type 1. However, the GAD test was not positive but within normal range. I thought to have type 1 diabetes you needed a positive GAD test. Will I develop a positive GAD in time?
A positive anti-GAD antibody titer is helpful in assigning a diagnosis of type 1 diabetes. However, a normal titer does not rule it out. Very often, the antibody titer can be positive at the time of diagnosis and revert to normal over time. Anti-GAD antibody appears to maintain a positive level longer than the others, but is not guaranteed to stay positive. In addition, when interpreting C peptide levels, it is important to make sure they are evaluated in light of the simultaneous glucose reading. For instance, a low C-peptide level at a time you are hypoglycemic is appropriate, compared to when you are hyperglycemic.
|Return to the Top of This Page|
Last Updated: Tuesday April 06, 2010 15:10:04
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.