Back to Ask the Diabetes Team Ask the Diabetes Team

From St. Louis, Missouri, USA:

Is it possible to mix Lispro and Regular together, in the same syringe? There have been situations that we felt would be ideal for our 5 year old daughter, where we wanted the more immediate Lispro to lower her sugars from a meal, especially one high in carbs, and then the regular to stick around and cover both protein and longer-to-break-down carbs. We have run into this situation, for example, at family events, parties etc., where she might be eating things we would not normally let her eat, and she would eat a meal, followed by a more sugary dessert than we would normally let her have. We would get really good late coverage with extra Regular, but she would have the immediate postprandial surge. Or, if we used Lispro, we would get lower immediate sugars, but then the blood glucose's would rise after the Lispro had peaked. We especially have noticed this when the occasion was at lunchtime, and it would be very difficult to figure out her morning NPH to have good coverage of the extra meal.

We just wondered if the two insulins had been tested together, and if this made any sense?


Although mixing lispro insulin [Humalog® brand] and Regular together have not been officially studied and approved, there have been several reports in the medical literature evaluating this combination. I am not aware that any adverse affects have been reported. I agree that sometimes the combination of these 2 insulins works better than either alone. Before making any changes, first be sure to discuss them with your child's own physician.


Original posting 1 Feb 98


  Back to Ask the Diabetes Team Return to the Top of This Page

Last Updated: Tuesday April 06, 2010 15:08:56
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.