From South Carolina, USA:
My cousin's daughter is 2 years, 7 months old. She was recently diagnosed with Type 1 diabetes. Upon coming home from the hospital, she favored her right leg and had a swollen right ankle. She was recently seen by an orthopedic doctor who, based upon a sedimentation rate of 40, believes she may have Juvenile Rheumatoid Arthritis. Just prior to the diagnosis of the diabetes, she had Lichen Striatus diagnosed. Aren't all of these disorders autoimmune in basis? Is there a syndrome or rare disorder that would cause this constellation of clinical events to emerge at this little girl's young age? Many thanks to you for your consideration and response to this question.
The triad that you describe has not been recognised as a syndrome. Type 1 Diabetes has of course been associated with other immune disorders, notably of the thyroid and with the celiac syndrome, Addison's Disease, and fasciitis of the palm. Juvenile Rheumatoid Arthritis, though an autoimmune disorder, does not seem to be part of that group. Lichen Striatus is more tenuously recognised as an immune disorder. This seems to be based on certain characteristics of the lymphocytes that infiltrate the skin lesions in this condition and partly on the resemblance clinically to the striated dermatosis sometimes seen in Disseminated Lupus, which is an immune disorder.
Original posting 8 Jun 97
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